By Annual Reviews
Read or Download Annual Review of Immunology Volume 9 1991 PDF
Best immunology books
Handbook of Dendritic Cells: Biology, Diseases and Therapies (3 Volume )
This can be the main finished instruction manual on dendritic cells, that includes an creation through Ralph M. Steinman and written by way of best specialists. In 3 volumes, it covers all facets from molecular telephone biology to scientific functions, highlighting the function of dendritic cells in battling melanoma, virus infections, and autoimmune ailments.
Natural Products for Neurodegenerative Diseases
Average items have lengthy been used for the comfort of neurological signs, but their mechanisms of motion stay elusive. fresh investigations have began to unveil the complicated molecular occasions linked to the healing results of normal items in neurodegenerative illnesses. during this ebook, top specialists proportion their views and most modern learn findings at the roles of traditional items in neuroprotection and neuronal regeneration.
Role of Apoptosis in Infection (Current Topics in Microbiology and Immunology)
This mechanism of programmed telephone loss of life performs a tremendous function in general improvement and regulate of telephone numbers in mature animals. Initiation of the apoptotic strategy can come from exterior or inner stimuli and is extremely regulated either via molecules that facilitate and via molecules that inhibit the method.
- Phagocyte-pathogen interactions : macrophages and the host response to infection
- Molecular Immunotoxicology
- B Cell Protocols (Methods in Molecular Biology)
- Oxford Handbook of Clinical Immunology and Allergy
- Neuroimmunomodulation: From Fundamental Biology to Therapy (Annals of the New York Academy of Sciences)
Additional info for Annual Review of Immunology Volume 9 1991
Example text
In contrast, T lymphocytesthat have been stimulated to proliferate culture show strong adhesion to nonantigen bearing cells. This antigenindependent adhesion is due to CD2and LFA-1on T lymphocytes interacting with LFA-3and ICAMson target cells, respectively (15, 28, 35, 36, 102). Althoughit was not clear in the original studies, antigen-independent adhesion requires prior activation of T lymphocytes since this type of spontaneous adhesion is low or absent when resting T lymphocytes are tested (5).
In contrast, neutrophils do not appear to express fl 1 integrins in significant amounts (59). T lymphocytes in LADpatients, alternatively, may selected to function in the absence of LFA-1. Mature T lymphocytes are selected in the thymus for recognition of self-MHCplus foreign antigens from large numbers of thymocyte clones expressing different TCR(60). Thymicepithelial cells and other componentsof the thymic stroma express ICAM-1, and interaction between normal thymocytes and thymic epithelial cells is mediated in part by LFA-1/ICAM-1 interaction (38, 61, 62).
70. 71. 72. 73. BENACERRAF responses in vitro. III. Tolerogenicproperties of the terpolymer L-glutamic acid6°-L-alanine3%L-tyrosine ~° (GAT) for ~pleen cells from nonresponder (H2~ and H-2q) mice. J. Exp. Med. 140: 172-84 Kapp, J. , Pierce, C. , Benacerraf, B. 1974. Genetic control of immuneresponses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by terpolymer L-glutamic acid6°-L-tyrosine ~° (GAT)~. J. Exp. Med. 140:648-59 Kapp, J. , Pierce, C. , Benacerraf, B. 1977. Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid 6°-L-alanine3°-L-tyrosine ~° (GAT).
