By Adriel R. Bonilla

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Extra resources for Antibiotic resistance : causes and risk factors, mechanisms and alternatives

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Acidophilus and L. reuteri were tested for antibiotic resistance by Sarra et al. (1982). All 16 isolates of L. reuteri were vancomycin- and polymycin B-resistant but only 4 out of 30 L. acidophilus strains were vancomycin-resistant. The inherent resistance of bifidobacteria to neomycin, nalixidic acid and polymycin B was reported by Miller and Finegold in 1976. This was further proven by Lim et al. (1993) when they assayed 37 natural bifidobacteria isolates against 18 different antibiotics. In another study, a total of 26 strains of Streptococcus cemoris and 12 strains of Streptococcus lactis were challenged with 18 antibiotics was performed by Orberg and Sandine in 1985.

The presence of antibiotics can induce and enhance gene transfer by providing a selective pressure for resistant bacteria to maintain and disseminate resistance genes (Courvalin, 2008). Horizontal Evolution – Gene Exchange Acquired resistance via horizontal evolution involves the development of resistance by the acquisition of new genetic material from other resistant organisms (Tenover, 2006). This gives rise to exogenous resistance, which is highly transferable (Courvalin, 2008). , 1999). The transfer of resistance elements can be promoted by several factors.

Species of the Lactobacillus group (L. acidophilus, L. gasseri, L. crispatus, L. johnsonii, L. delbrueckii and L. , 2007). The vancomycin resistance appeared to be strain-specific, in which the MIC for L. rhamnosus, L. plantarum and L. paracasei was more than 256 µg/ml, while it was less than 2 µg/ml for L. acidophilus (Danielsen and Wind, 2003). , 2005). , 2008). , 1999). E. faecium isolated from food or patients have highly variable resistance profiles, even though many are acquired traits (Mathur and Singh, 2005).

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